Nature publication with SFB contribution: Part of the avian retina functions permanently without oxygen
January 21, 2026 Neural tissue typically depends on a rich blood supply, yet birds present a striking exception: their retina, one of the most energy-demanding neural tissues, lacks internal blood vessels. A new study led by researchers from Aarhus university together with SFB researchers Karin Dedek and Henrik Mouritsen shows that while the outer retina receives oxygen, the inner retina functions under chronic anoxia, sustained by anaerobic glycolysis. A specialized structure called the 'pecten' appears to solve this paradox by delivering glucose to the retina and removing lactic acid. This unusual metabolic arrangement may have enabled the evolution of a thick, avascular retina and later provided birds with a visual advantage during high-altitude flight.
To learn more, watch our SciCom video on this surprising finding and read the press release from University of Oldenburg.
Damsgaard C, Skøtt MV, Williams CJA, [...], Dedek K, [...], Mouritsen H, et al. Oxygen-free metabolism in the bird inner retina supported by the pecten. Nature. 2026 Jan 21. doi:10.1038/s41586-025-09978-w.








